Use of botulinum toxin for rosacea: a pilot study

Introduction: Rosacea is a chronic inflammatory skin disease.The intradermal application of botulinum toxin (BT) has been studied as a therapeutic option for patients who struggle to manage flushing and/or persistent facial erythema.There is no standard protocol for BT application in rosacea.Objective: To evaluate the effectiveness of botulinum toxin application on erythematotelan-giectatic rosacea.

Methods: Pilot study with case series.We applied intradermal GOAT WHOLE MILK BT in 10 patients with a diagnosis of rosacea and symptoms of persistent erythema and/or facial flushing.Patients received 10 to 15 injections per hemiface (1 unit of onabotulinum BT per injection) and 0 to 5 injections in the nasal region, totaling 25 to 35 units per patient.Results: Seventy-five Hand Care Set percent of the patients presented a reduction in flush and erythema intensity.

The follow-up time was three months, and no serious adverse events were observed.Conclusions: The therapeutic arsenal to control erythema and facial flushing of rosacea, especially refractory to the usual treatment, should consider the intradermal application of BT type A.

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